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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
18.18
Human Site:
Y359
Identified Species:
28.57
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
Y359
H
S
P
Y
P
E
E
Y
A
R
L
G
R
L
Y
Chimpanzee
Pan troglodytes
XP_511869
806
91579
Y554
H
S
P
Y
P
E
E
Y
A
R
L
G
R
L
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
K320
E
F
C
L
K
Y
M
K
S
Q
T
I
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
Y361
H
S
P
Y
P
E
E
Y
A
R
L
G
R
L
Y
Rat
Rattus norvegicus
Q810T5
612
70496
Y360
H
S
P
Y
P
E
E
Y
A
R
L
G
R
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
Y359
H
S
P
Y
P
E
E
Y
A
R
L
G
R
L
Y
Frog
Xenopus laevis
NP_001079995
617
71123
S359
E
L
D
T
W
Y
H
S
P
Y
P
E
E
Y
A
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
M333
C
E
F
C
L
K
Y
M
K
S
Q
T
I
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
R306
K
S
R
K
C
L
E
R
H
L
S
K
C
N
L
Honey Bee
Apis mellifera
XP_392324
916
101344
F651
Q
S
P
Y
P
E
E
F
S
R
A
P
K
L
Y
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
K223
C
L
K
R
H
M
E
K
C
A
M
C
H
P
P
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
K269
L
T
E
D
V
K
V
K
S
R
Q
H
R
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
N210
F
F
C
E
F
C
L
N
F
M
K
R
K
E
Q
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
Q210
Q
Y
F
G
S
K
K
Q
Y
E
R
Y
R
K
K
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
R271
G
E
L
K
S
F
V
R
H
R
Q
K
C
T
L
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
100
0
6.6
N.A.
13.3
60
6.6
13.3
P-Site Similarity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
N.A.
100
0
13.3
N.A.
13.3
80
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
34
7
7
0
0
0
7
% A
% Cys:
14
0
14
7
7
7
0
0
7
0
0
7
14
0
0
% C
% Asp:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
14
14
7
7
0
40
54
0
0
7
0
7
7
14
7
% E
% Phe:
7
14
14
0
7
7
0
7
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
0
0
0
0
0
0
0
34
0
0
0
% G
% His:
34
0
0
0
7
0
7
0
14
0
0
7
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% I
% Lys:
7
0
7
14
7
20
7
20
7
0
7
14
14
7
7
% K
% Leu:
7
14
7
7
7
7
7
0
0
7
34
0
7
47
14
% L
% Met:
0
0
0
0
0
7
7
7
0
7
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% N
% Pro:
0
0
40
0
40
0
0
0
7
0
7
7
0
7
7
% P
% Gln:
14
0
0
0
0
0
0
7
0
7
20
0
0
0
7
% Q
% Arg:
0
0
7
7
0
0
0
14
0
54
7
7
47
7
14
% R
% Ser:
0
47
0
0
14
0
0
7
20
7
7
0
0
0
0
% S
% Thr:
0
7
0
7
0
0
0
0
0
0
7
7
0
7
0
% T
% Val:
0
0
0
0
7
0
14
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
40
0
14
7
34
7
7
0
7
0
7
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _